Thursday, March 6, 2008

Does Infant/Mother Nutrition Affect Allergy-Related Problems?

1. The idea that egg, fish, and foods containing peanut protein should not be introduced before 1 year of age is not based on good science.
2. Maternal dietary restrictions during pregnancy do not appear to play a significant role in the prevention of atopic [allergy-related] disease in infants.
3. There is no convincing evidence for the use of soy-based infant formula for the purpose of allergy prevention.
4. For infants beyond 4-6 months of age, there is insufficient data to support a protective effect of any dietary intervention for the development of atopic disease.
5. In Infants who are at risk of developing atopic disease, the current evidence does not support the hypothesis that exclusive breast-feeding protects against allergic asthma occurring beyond the age of 6 years.
6. For a child who has developed an atopic disease that might be precipitated or exacerbated by ingested proteins (via human milk, infant formula, or specific complementary foods), treatment could require specific identification and restriction of causal food proteins .
Dust mites, roaches can weaken skin barrier: study

HONG KONG (Reuters)
Dust mites and cockroach allergens can weaken defense mechanisms of the human skin, making it more permeable and vulnerable, a study in South Korea has found.
In an article in the latest issue of the Journal of Investigative Dermatology, researchers said it was important, especially for people with eczema, to protect themselves from such microscopic bugs and filth.
Cockroach allergens are particles of feces, saliva and other matter found on the bodies of these insects.
In the study, the researchers disrupted the skin barrier function of a group of volunteers by repeatedly sticking cellophane tape on a part of their forearm and then stripping it off. They were then exposed to roach allergens and dust mites.
These particles were later found to have triggered a receptor in the skin, known as PAR-2, which delayed the skin repair process.
"The skin barrier function is already damaged in eczema patients and it has to repair itself. But allergens like dust mite and cockroach allergens will delay the repair function," said Jeong Se Kyoo, senior researcher at Neopharm Co. Ltd.
"Then more allergens will penetrate the skin, it's a vicious cycle," he said in a telephone interview.
Over 15 million Americans suffer from eczema, a chronic skin condition characterized by dry patches of very itchy skin. The most common form, atopic dermatitis, affects between 10 and 20 percent of the world's population at some point during childhood.
(Reporting by Tan Ee Lyn; Editing by Sugita Katyal)